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Plasma Amyloid-β Oligomerization Tendency Predicts Amyloid PET Positivity.

Jung-Min PyunJi Sun RyuRyan LeeKyu Hawn ShimYoung Chul YounNayoung RyooSang-Won HanYoung Ho ParkSungmin KangSeong Soo Alexander AnSang Yun Kim
Published in: Clinical interventions in aging (2021)
The Aβ oligomerization tendency in plasma could predict amyloid PET positivity with high performance, and, when it is combined with age, MMSE score, and APOE ε4 status, predictability was improved substantially. This suggests the potential of MDS-OAβ as a useful initial stage test in the clinical and research fields of AD.
Keyphrases
  • pet ct
  • computed tomography
  • positron emission tomography
  • pet imaging
  • high fat diet
  • cognitive decline
  • metabolic syndrome
  • type diabetes
  • adipose tissue
  • human health
  • climate change
  • risk assessment
  • skeletal muscle