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Weak base drug-induced endolysosome iron dyshomeostasis controls the generation of reactive oxygen species, mitochondrial depolarization, and cytotoxicity.

Peter W HalcrowDarius N K QuansahNirmal KumarRebecca L SollowayKayla M TeigenKasumi A LeeBraelyn LiangJonathan D Geiger
Published in: NeuroImmune pharmacology and therapeutics (2024)
interorganellar signaling may improve pharmacotherapeutics.
Keyphrases
  • drug induced
  • reactive oxygen species
  • liver injury
  • oxidative stress
  • adverse drug
  • iron deficiency
  • electronic health record