Low probability of disease cure in advanced ovarian carcinomas before the PARP inhibitor era.

Benoit YouLilian Van WagensveldMichel TodGabe S SonkeHugo Mark HorlingsR F P M KruitwagenAndreas Du BoisFrédéric SelleTimothy PerrenJacobus PfistererFlorence JolyAdrian CookMarie Christine KaminskyKerstin WollschlaegerAlain LortholaryOliver TomeAlexandra LearyGilles FreyerMaaike Van Der AaOlivier Colomban

Published in: British journal of cancer (2022)

The probability of LDF > 5 years after first-line treatment in 3486 patients (<4%) was lower than thought. These data could represent a reference for future studies meant to assess progress related to PARP inhibitors.

Keyphrases

dna damage
dna repair
electronic health record
current status
high grade
case control
oxidative stress
machine learning
data analysis
artificial intelligence