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Assessing actionability and incidental findings of germline variants in two precision oncology trials.

Maria Baz IbrahimYahia AdnaniGérôme Jules ClémentLudovic LacroixYohann LoriotBenjamin BesseChristophe MassardEtienne Rouleau
Published in: European journal of cancer (Oxford, England : 1990) (2024)
Our study underscores the significance of germline sequencing in identifying actionable alterations and the need for improved variant interpretation as well as pretest counseling plans in precision oncology trials.
Keyphrases
  • palliative care
  • dna repair
  • single cell
  • copy number
  • dna damage
  • oxidative stress
  • hiv testing
  • hepatitis c virus
  • human immunodeficiency virus