Temporal trends in dietary creatine intake from 1999 to 2018: an ecological study with 89,161 participants.

Our findings suggest a variation in dietary creatine intake in the U.S. population during the past 20 years, with young persons tend to consume fewer grams of creatine per day from 1999 onwards. Long-running studies are highly warranted to assess possible health consequences of variable creatine intake in human nutrition.