Non-alcoholic fatty liver disease is associated with coronary flow reserve impairment: A pilot meta-analysis.
Hritvik JainNeha PervezDebankur DeyFatima Ali RazaJyoti JainMushood AhmedAman GoyalRamez M OdatMayank JhaMuhammad Daoud TariqSebastian FoxRukesh YadavRaheel AhmedPublished in: Medicine (2024)
Patients with NAFLD are at a higher risk of coronary microvascular dysfunction, as demonstrated by reduced CFRV and hyperemic DPFV. The presence of abnormal coronary flow reserve in patients with NAFLD provides insights into the higher rates of cardiovascular disease in these patients. Early aggressive targeted interventions for impaired coronary flow reserve in subjects with NAFLD may lead to improvement in clinical outcomes.
Keyphrases
- coronary artery disease
- coronary artery
- cardiovascular disease
- systematic review
- end stage renal disease
- ejection fraction
- aortic stenosis
- chronic kidney disease
- newly diagnosed
- type diabetes
- physical activity
- cardiovascular events
- prognostic factors
- peritoneal dialysis
- oxidative stress
- heart failure
- cancer therapy
- meta analyses
- study protocol
- aortic valve
- atrial fibrillation
- case control
- double blind