Genomic analysis of virulence factors and antimicrobial resistance of group B Streptococcus isolated from pregnant women in northeastern Mexico.
Gerardo Del Carmen Palacios-SaucedoLydia Guadalupe Rivera-MoralesJosé Manuel Vázquez-GuillénAmilcar Caballero-TrejoMelissa Carolina Mellado-GarcíaAldo Sebastián Flores-FloresJosé Alfredo González-NavarroCelia Geovana Herrera-RiveraLuis Ernesto Osuna-RosalesJulio Antonio Hernández-GonzálezRicardo Vázquez-JuárezCarolina Barrón-EnríquezRamón Valladares-TrujilloJoaquín Darío Treviño BáezCésar Alejandro Alonso-TéllezLuis Daniel Ramírez-CalvilloRicardo Martín Cerda-FloresRocío Ortiz-LópezMiguel Ángel Rivera-AlvaradoFortino Solórzano-SantosJorge Castro-GarzaCristina Rodríguez-PadillaPublished in: PloS one (2022)
The low prevalence of colonization and the non-occurrence of mother-to-child transmission suggest that the intentional search for GBS colonization in this population is not justified. Our results also suggest that risk factors should guide the use of intrapartum antibiotic prophylaxis. The detection of strains with genes coding virulence factors means that clones with pathogenic potential circulates in this region. On the other hand, the identification of decreased susceptibility to antibiotics from different antimicrobial categories shows the importance of adequately knowing the resistance patterns to prevent and to treat GBS perinatal infection.
Keyphrases
- antimicrobial resistance
- pregnant women
- risk factors
- escherichia coli
- staphylococcus aureus
- biofilm formation
- bioinformatics analysis
- pseudomonas aeruginosa
- mental health
- risk assessment
- genome wide
- candida albicans
- gene expression
- cystic fibrosis
- transcription factor
- loop mediated isothermal amplification
- quantum dots
- sensitive detection