A Portable Wireless Intelligent Nanosensor for 6,7-Dihydroxycoumarin Analysis with A Black Phosphorene and Nano-Diamond Nanocomposite-Modified Electrode.
Xiaoqing LiLisi WangLijun YanXiao HanZejun ZhangXiaoping ZhangWei SunPublished in: Biosensors (2023)
In this work, a novel portable and wireless intelligent electrochemical nanosensor was developed for the detection of 6,7-dihydroxycoumarin (6,7-DHC) using a modified screen-printed electrode (SPE). Black phosphorene (BP) nanosheets were prepared via exfoliation of black phosphorus nanoplates. The BP nanosheets were then mixed with nano-diamond (ND) to prepare ND@BP nanocomposites using the self-assembly method, achieving high environmental stability. The nanocomposite was characterized by SEM, TEM, Raman, XPS and XRD. The nanocomposite was used for the modification of SPE to improve its electrochemical performances. The nanosensor displayed a wide linear range of 0.01-450.0 μmol/L with a low detection limit of 0.003 μmol/L for 6,7-DHC analysis. The portable and wireless intelligent electrochemical nanosensor was applied to detect 6,7-DHC in real drug samples by the standard addition method with satisfactory recoveries, which extends the application of BP-based nanocomposite for electroanalysis.
Keyphrases
- reduced graphene oxide
- gold nanoparticles
- label free
- carbon nanotubes
- low cost
- quantum dots
- solid phase extraction
- visible light
- molecularly imprinted
- highly efficient
- ms ms
- ionic liquid
- real time pcr
- loop mediated isothermal amplification
- high throughput
- emergency department
- aqueous solution
- metal organic framework
- tandem mass spectrometry
- heavy metals
- human health
- data analysis
- anaerobic digestion