Identification of PEPT2 as an important candidate molecule in 5-ALA-mediated fluorescence-guided surgery in WHO grade II/III gliomas.

Chongxian HouShigeru YamaguchiYukitomo IshiShunsuke TerasakaHiroyuki KobayashiHiroaki MotegiKanako C HatanakaKiyohiro Houkin

Published in: Journal of neuro-oncology (2019)

The results suggest PEPT2 is an important candidate molecule in 5-ALA-mediated FGS in grade II/III gliomas. As the overexpression of PEPT2 was associated with higher PpIX fluorescence intensity, PEPT2 may improve fluorescence-guided resection in grade II/III gliomas.

Keyphrases

high grade
single molecule
energy transfer
cell proliferation
coronary artery bypass
transcription factor
coronary artery disease
percutaneous coronary intervention
acute coronary syndrome
quantum dots