Differences in circulating alpha-calcitonin gene-related peptide levels in inflammatory bowel disease and its relation to migraine comorbidity: A cross-sectional study.

Marta Pascual Gabriel GárateVicente González-QuintanillaJorge Madera-FernándezBeatriz CastroMaría José GarcíaJavier CrespoMontserrat RiveroJulio Pascual

Published in: Headache (2024)

Together with CM, circulating alpha-CGRP levels are different in patients with IBD, perhaps reflecting a chronic inflammatory state. IBD is an example of how alpha-CGRP levels are not a totally specific migraine biomarker. However, alpha-CGRP levels were further increased in patients with IBD who have a history of migraine, which reinforces its role as a biomarker in migraine patients, always bearing in mind their comorbidities.

Keyphrases

ejection fraction
newly diagnosed
oxidative stress
physical activity
gene expression
copy number
risk factors
dna methylation
transcription factor