Alpha-2 Adrenoreceptor Antagonist Yohimbine Potentiates Consolidation of Conditioned Fear.
Matthias F J SperlChristian PanitzNadine SkoludaUrs Markus NaterDiego A PizzagalliChristiane HermannErik M MuellerPublished in: The international journal of neuropsychopharmacology (2022)
These results suggest that yohimbine potentiates cardiac and central electrophysiological signatures of fear memory consolidation. They thereby elucidate the key role of noradrenaline in strengthening the consolidation of conditioned fear associations, which may be a key mechanism in the etiology of fear-related disorders.