Induced pluripotent stem cell-derived cardiomyocyte (iPSC-CM) therapy has emerged as a highly promising field of heart repair. Lin et al. 1 presented compelling evidence on the long-term engraftment and maturation of autologous iPSC-CMs in two rhesus macaques, demonstrating unprecedented cardiac autografting data in large animal models without the need of immunosuppressants.
Keyphrases
- high glucose
- endothelial cells
- angiotensin ii
- induced pluripotent stem cells
- cell therapy
- heart failure
- left ventricular
- electronic health record
- diabetic rats
- bone marrow
- big data
- drug induced
- anterior cruciate ligament reconstruction
- platelet rich plasma
- oxidative stress
- mesenchymal stem cells
- machine learning
- hematopoietic stem cell
- data analysis