Genetic etiologic analysis in 74 Chinese Han women with idiopathic premature ovarian insufficiency by combined molecular genetic testing.

Jiandong ShenDianyun QuYan GaoFangxi SunJiazi XieXueping SunDaowu WangXiang MaYugui CuiJiayin LiuFeiyang Diao

Published in: Journal of assisted reproduction and genetics (2021)

This study suggested targeted NGS was an efficient etiologic test for idiopathic POI patients without FMR1 premutation and enriched the variant spectrum of POI-related genes.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
genome wide
gene expression
patient reported outcomes
copy number
dna methylation
patient reported