Cardiovascular adverse events associated with immune checkpoint inhibitors: A retrospective multicenter cohort study.
Yi ZhengZiliang ChenWenhua SongYu XuZhiqiang ZhaoYihong SunYuanyuan WangXuhong GengJun ZhaoXiaowei ZhangYanmin XuJeffrey Shi Kai ChanGary TseGuangping LiLili HongTong LiuPublished in: Cancer medicine (2024)
Elevated CK-MB after ICI treatment is the independent risk factor for the incidence of ICI-associated myocarditis, and elevated cTnI and NLR after ICI treatment are the independent risk factors for the development of ICI-associated severe myocarditis. CK-MB, cTnI, and NLR demonstrated a promising predictive utility for the identification of ICI-associated myocarditis and severe myocarditis.