Evaluation of Antihyperglycemic Effect of Extract of Moringa stenopetala (Baker f.) Aqueous Leaves on Alloxan-Induced Diabetic Rats.

Samuel WoldekidanAbay MuluWondwossen ErgetieFrehiwot TekaAsfaw MeressaAshenif TadeleAbiy AbebeWorku GemechuNegero Gemeda Rekik Ashebir Muluye Meron Sileshi Yoseph Tolcha

Published in: Diabetes, metabolic syndrome and obesity : targets and therapy (2021)

It is possible to conclude that oral administration of Moringa stenopetala (Baker f.) aqueous leaf extracts (250mg/kg and 500mg/kg) for 28 days showed beneficial effects on antihyperglycemia, improved body weight and Alloxan damaged pancreatic β-cells, and restored biochemical changes.

Keyphrases

diabetic rats
oxidative stress
body weight
induced apoptosis
ionic liquid
cell cycle arrest
endoplasmic reticulum stress
signaling pathway
cell death
high glucose
pi k akt