Comparative risk of serious hypoglycemia with oral antidiabetic monotherapy: A retrospective cohort study.

Charles E LeonardXu HanColleen M BrensingerWarren B BilkerSerena CardilloJames H FlorySean Hennessy

Published in: Pharmacoepidemiology and drug safety (2017)

Sulfonylureas were associated with the highest rates of serious hypoglycemia. Among all study drugs, the highest rate was seen with glyburide. Pioglitazone was associated with a lower adjusted hazard for serious hypoglycemia vs metformin, while rosiglitazone and nateglinide had hazards similar to that of metformin.

Keyphrases

type diabetes
glycemic control
metabolic syndrome
insulin resistance
study protocol