Within-household clustering of genetically related Plasmodium falciparum infections in a moderate transmission area of Uganda.

Jessica J BriggsAlison KuchtaMax MurphySofonias TessemaEmmanuel ArinaitweJohn RekAnna ChenJoaniter I NankabirwaChris DrakeleyDavid SmithTeun BousemaMoses KamyaIsabel Rodriguez-BarraquerSarah StaedkeGrant DorseyPhilip J RosenthalBryan Greenhouse

Published in: Malaria journal (2021)

Genetic data from a relatively small number of diverse, multiallelic loci reflected fine scale patterns of malaria transmission. Given the increasing interest in applying genetic data to augment malaria surveillance, this study provides evidence that genetic data can be used to inform transmission patterns at local spatial scales even in moderate transmission areas.

Keyphrases

plasmodium falciparum
genome wide
electronic health record
big data
copy number
public health
air pollution
dna methylation
machine learning
data analysis
rna seq
deep learning
genome wide association study
genome wide association