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Immunotherapeutic advances in glioma management: The rise of vaccine-based approaches.

Wireko Andrew AwuahMuhammad Hamza ShahJoecelyn Kirani TanSruthi RanganathanVivek SankerKwadwo DarkoPearl Ohenewaa TenkorangBryan Badayelba AdagebaArjun AhluwaliaVallabh ShetNicholas AderintoMrinmoy KunduToufik Abdul-RahmanOday Atallah
Published in: CNS neuroscience & therapeutics (2024)
Addressing the challenges associated with glioma vaccines involves exploring combination therapies, targeted approaches, and personalized medicine. Combining vaccines with traditional therapies like radiotherapy or chemotherapy may enhance efficacy by boosting the immune system's ability to fight tumor cells. Personalized vaccines tailored to individual patient profiles present an opportunity for improved outcomes. Furthermore, global collaboration and equitable distribution are critical for ensuring access to glioma vaccines, especially in low- and middle-income countries with limited healthcare resources CONCLUSION: Glioma vaccines represent a promising avenue in the fight against gliomas, offering hope for improving patient outcomes in a disease that is notoriously difficult to treat. Despite the challenges, continued research and the development of innovative strategies, including combination therapies and personalized approaches, are essential for overcoming current barriers and transforming the treatment landscape for glioma patients.
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