Login / Signup

Enhanced DNA Sensing and Chiroptical Performance by Restriction of Double-Bond Rotation of AIE cis-Tetraphenylethylene Macrocycle Diammoniums.

Ying-Xue YuanHong-Chao ZhangMing HuQi ZhouBai-Xing WuFu-Ling WangMing Hua LiuYan-Song Zheng
Published in: Organic letters (2020)
The aggregation-induced emission (AIE) mechanism of restriction of double-bond rotation (RDBR) was utilized to design an excellent solid emitter and sensor for the first time. Thus, cis-tetraphenylethylene (TPE) macrocycle diammoniums were synthesized and bound to a DNA chain by its two ammonium arms. The formed TPE dicycle at the cis position restricted the rotation of the double bond in both the ground and excited states, resulting in AIE enhancement, chiroptical performance enhancement, and sensing enhancement.
Keyphrases
  • fluorescent probe
  • living cells
  • single molecule
  • circulating tumor
  • cell free
  • nucleic acid
  • quantum dots