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Assessment of BCG and inactivated Mycobacterium bovis vaccines in an experimental tuberculosis infection model in sheep.

Ana BalseiroRaúl AltuzarraEnric VidalXavier MollYvonne EspadaIker A SevillaMariano DomingoJoseba M GarridoRamón A JusteMiguel PrietoBernat Pérez de Val
Published in: PloS one (2017)
This study proposes a reliable new experimental model for a better understanding of tuberculosis in sheep. BCG vaccination offers an effective prospect for controlling the disease. Moreover alternative doses and/or routes of administration should be considered to evaluate the efficacy of the HIMB vaccine candidate.
Keyphrases
  • mycobacterium tuberculosis
  • pulmonary tuberculosis
  • hiv aids
  • emergency department
  • adverse drug
  • antiretroviral therapy
  • clinical evaluation