Corticospinal fibers with different origins impair in amyotrophic lateral sclerosis: A neurite orientation dispersion and density imaging study.

Nao-Xin HuangWen QinJia-Hui LinQiu-Yi DongHua-Jun Chen

Published in: CNS neuroscience & therapeutics (2023)

Microstructural impairment of CST subfibers (especially those originating from M1) is the key feature of ALS. The combination of NODDI and CST subfibers analysis may improve diagnosing performance for ALS.

Keyphrases

amyotrophic lateral sclerosis
high resolution
machine learning
white matter
deep learning
mass spectrometry