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Antimicrobial activities of saponins from Melanthera elliptica and their synergistic effects with antibiotics against pathogenic phenotypes.

Cyrille Ngoufack TagousopJean-de-Dieu TamokouIrene Chinda KengneDavid NgnokamLaurence Voutquenne-Nazabadioko
Published in: Chemistry Central journal (2018)
The present study showed significant antimicrobial activity of compounds 1, 2, 3 and 4 against the tested microorganisms. The saponins act in synergy with the tested standard antibiotics. This synergy could lead to new options for the treatment of infectious diseases and emerging drug resistance.
Keyphrases
  • infectious diseases
  • staphylococcus aureus
  • drug delivery
  • replacement therapy