Towards harmonizing clinical linear energy transfer (LET) reporting in proton radiotherapy: a European multi-centric study.

Christian HahnJakob ÖdénAlexandru DasuAnne VestergaardMaria Fuglsang JensenOlga SokolClaudia PardiFaiza BourhalebAmélia LeiteLudovic de MarziEdward SmithAdam AitkenheadChristopher RoseMichael MerchantKaren KirkbyLeszek GrzankaJörg PawelkeArmin Lühr

Published in: Acta oncologica (Stockholm, Sweden) (2021)

Harmonizing the reported LET among PT centers is feasible and allows for consistent multi-centric analysis and reporting of tumor control and toxicity in view of a variable RBE. It may serve as basis for harmonized variable RBE dose prescription in PT.

Keyphrases

energy transfer
adverse drug
early stage
quantum dots
radiation therapy
oxidative stress
emergency department
radiation induced