Genetic analysis for type 1 diabetes genes in juvenile dermatomyositis unveils genetic disease overlap.

Hui-Qi QuJingchun QuCourtney VaccaroXiao ChangFrank MentchJin LiFernanda MafraKenny NguyenMichael GonzalezMichael MarchRenata PellegrinoJoseph GlessnerPatrick SleimanCharlly KaoHakon H Hakonarson

Published in: Rheumatology (Oxford, England) (2022)

Novel mechanisms of JDM related to these T1D genes are suggested by this study, which may imply novel therapeutic targets for JDM and warrant further study.

Keyphrases

type diabetes
genome wide
cardiovascular disease
rheumatoid arthritis
dna methylation
adipose tissue
skeletal muscle
copy number
weight loss