Effect of short-term storage of blood samples on gene expression in lung cancer patients.

Eva ObermayrNina KoppensteinerNicole HeinzlEva SchusterBarbara HolzerHannah FabikanChristoph WeinlingerOliver IlliniMaximilian J HochmairRobert Zeillinger

Published in: Clinical chemistry and laboratory medicine (2022)

The study demonstrates the surprising stability of CTC-related transcripts, which makes overnight shipping of native blood samples possible. Careful verification is required when using model systems - such as normal blood spiked with tumor cells - or other CTC-related markers, as individual transcripts may respond differently to storage.

Keyphrases

gene expression
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
circulating tumor cells
prognostic factors