Ruxolitinib withdrawal complicating emergency aortic root replacement.
Malgorzata Maggie SzpytmaDamian Joseph GimpelGareth Weijie CrouchJayme S BennettsPublished in: Interactive cardiovascular and thoracic surgery (2022)
Ruxolitinib, a Janus kinase inhibitor, is associated with severe withdrawal phenomena. Adequate tapering is often underemphasized in surgical emergencies and can complicate the postoperative course. We present a case of acute ruxolitinib withdrawal in a gentleman undergoing emergency cardiac surgery.
Keyphrases
- cardiac surgery
- public health
- emergency department
- aortic dissection
- healthcare
- liver failure
- acute kidney injury
- drug induced
- patients undergoing
- respiratory failure
- aortic valve
- left ventricular
- early onset
- pulmonary artery
- intensive care unit
- coronary artery
- extracorporeal membrane oxygenation
- pulmonary arterial hypertension