Is the Leptin/Adiponectin Ratio a Better Diagnostic Biomarker for Insulin Resistance than Leptin or Adiponectin Alone in Adolescents?

César A Agostinis-SobrinhoSofia E de Castro Ferreira VicenteSigute NorkieneAlona Rauckienė-MichaelssonJustina KievišienėViney Prakash DubeyArturas Razbadauskas Luís Lopes Rute Santos

Published in: Children (Basel, Switzerland) (2022)

Leptin and L/A ratio were associated with IR risk, after adjustments for confounders in both sexes and adiponectin in girls. The L/A ratio seems to have a higher diagnostic accuracy to identify IR risk than adiponectin or leptin, in both sexes.

Keyphrases

insulin resistance
metabolic syndrome
adipose tissue
high fat diet
skeletal muscle
polycystic ovary syndrome
young adults
type diabetes
high fat diet induced
physical activity