Safe Administration of Ipilimumab, Pembrolizumab, and Nivolumab in a Patient with Metastatic Melanoma, Psoriasis, and a Previous Guillain-Barré Syndrome.
Alessio CortelliniAlessandro ParisiMaria Concetta FargnoliKatia CannitaAzzurra IrelliGiampiero PorzioClaudio MartinazzoCorrado FicorellaPublished in: Case reports in oncological medicine (2018)
This case report supports that although a history of immune disorders is one of the major risk factors for development of irAEs, in some patients, it could be possible to safely administer sequential treatments with ICIs. A proper decision should be made, considering therapeutic options, disease-related risks, and those related to a recurrence of preexisting autoimmune disorders.