Efficacy of Immune Checkpoint Inhibition and Cytotoxic Chemotherapy in Mismatch Repair-Deficient and Microsatellite Instability-High Pancreatic Cancer: Mayo Clinic Experience.

Tucker W Coston Aakash P Desai Hani M Babiker Mohamad Bassam B Sonbol Sakti Cjakrabarti Amit Mahipal Robert R McWilliams Wen Wee Ma Tanios S Bekaii-Saab John A Stauffer Jason S Starr

Published in: JCO precision oncology (2023)

Our data argue for the preferential use of ICI over cytotoxic chemotherapy in any patient with dMMR/MSI-H PC requiring systemic therapy, including in the metastatic and adjuvant/neoadjuvant settings.

Keyphrases

locally advanced
squamous cell carcinoma
rectal cancer
small cell lung cancer
early stage
primary care
radiation therapy
lymph node
case report
big data
machine learning
cell therapy