Diffusion-Weighted MR Imaging in a Prospective Cohort of Children with Cerebral Malaria Offers Insights into Pathophysiology and Prognosis.
Sarah Mohajeri MoghaddamGretchen L BirbeckTerrie E TaylorKarl B SeydelS D KampondeniMichael J PotchenPublished in: AJNR. American journal of neuroradiology (2019)
Restricted diffusion is common in pediatric cerebral malaria. Isolated subcortical white matter diffusion restriction is a unique imaging pattern associated with less severe disease and a good prognosis for full recovery. The underlying pathophysiology may be related to selective white matter vulnerability.
Keyphrases
- white matter
- diffusion weighted
- contrast enhanced
- plasmodium falciparum
- multiple sclerosis
- subarachnoid hemorrhage
- magnetic resonance imaging
- high resolution
- computed tomography
- magnetic resonance
- climate change
- young adults
- cerebral ischemia
- early onset
- cerebral blood flow
- drug induced
- mass spectrometry
- photodynamic therapy