Dimethyl fumarate preserves brainstem and cervical spinal cord integrity in radiologically isolated syndrome.
Darin T OkudaChristina J AzevedoDaniel PelletierTatum M MoogSaeed MoazamiSepideh RezvaniFrancesca BovisMaria Pia SormaniAksel SivaOrhun KantarciChristine Lebrun-Frénaynull nullPublished in: Journal of neurology (2024)
The benefit of disease-modifying therapy in RIS may extend to CNS structures impacted by neurodegeneration that is below the resolution of conventional volumetric measures.