Levothyroxine treatment and gastric juice pH in humans: the proof of concept.
Camilla ViriliGiovanni BrunoMaria Giulia SantaguidaLucilla GarganoIlaria StramazzoCorrado De VitoAlessia CiceniaGiulia ScaleseBarbara PorowskaCarola SeveriPierpaolo TrimboliPublished in: Endocrine (2022)
The in vivo measurement of gastric pH highlighted its key role in determining the minimal effective dose of oral T4 and may explain the interference of food, of some drugs and gut disorders on levothyroxine treatment.
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