LINC02381-ceRNA exerts its oncogenic effect through regulation of IGF1R signaling pathway in glioma.

Hossein NematiMasoumeh Fakhre-TahaAmir-Reza JavanmardAmin JahanbakhshiSeyed Javad MowlaBahram Mohammad Soltani

Published in: Journal of neuro-oncology (2022)

The overall results indicated that LINC02381 exerts its oncogenic effect in glioma cells through sponging miR-128 and miR-150 to upregulate the IGF1R signaling pathway. Our results introduce LINC02381 and miR-128, and miR-150 as potential prognosis and therapy targets for the treatment of glioma.

Keyphrases

long non coding rna
cell proliferation
long noncoding rna
pi k akt
signaling pathway
transcription factor
epithelial mesenchymal transition
induced apoptosis
human health
combination therapy