DZNep promotes mouse bone defect healing via enhancing both osteogenesis and osteoclastogenesis.

Xiankun CaoWenxin HeKewei RongShenggui XuZhiqian ChenYuwei LiangShuai HanYifan ZhouXiao YangHui MaAn QinJie Zhao

Published in: Stem cell research & therapy (2021)

DZNep targeting EZH2-H3K27me3 axis facilitated the healing of mice bone defect via simultaneously enhancing osteoclastic bone resorption and promoting osteoblastic bone formation.

Keyphrases

bone loss
bone mineral density
bone regeneration
soft tissue
postmenopausal women
long non coding rna
body composition
type diabetes
metabolic syndrome
lps induced
insulin resistance