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How long is too long: A retrospective study evaluating the impact of the duration of noninvasive oxygenation support strategies (high flow nasal cannula & BiPAP) on mortality in invasive mechanically ventilated patients with COVID-19.

Aditya KasarabadaKimberly BarkerTheresa GanoeLindsay ClevengerCristina ViscoJessica GibsonRahim KarimiNegar NaderiBrian LamMaria StepanovaLinda HenryChristopher S KingMehul Desai
Published in: PloS one (2023)
Time spent on noninvasive oxygenation support [as defined by high flow nasal cannula (HFNC) and BiPAP] prior to IMV increased mortality risk. Research for the generalizability of our findings to other respiratory failure patient populations is needed.
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