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Relationship between improvement of glycaemic control and reduction of major cardiovascular events in 15 cardiovascular outcome trials: A meta-analysis with meta-regression.

Dario GiuglianoGiuseppe BellastellaMiriam LongoLorenzo ScappaticcioMaria Ida MaiorinoPaolo ChiodiniKatherine Esposito
Published in: Diabetes, obesity & metabolism (2020)
The blood glucose reduction observed in CVOTs may play some role in reducing the risk of non-fatal stroke, at least during treatment with GLP-1RAs, without affecting the other two components of MACE.
Keyphrases
  • cardiovascular events
  • blood glucose
  • coronary artery disease
  • cardiovascular disease
  • glycemic control
  • type diabetes
  • atrial fibrillation
  • blood pressure
  • wild type
  • cerebral ischemia