Treatment of ovarian clear cell carcinoma with immune checkpoint blockade: a case series.

Tiffany Y SiaBeryl L Manning-GeistSushmita GordhandasRajmohan MuraliAntonio MarraYing L LiuClaire F FriedmanTravis J HollmannOliver ZivanovicDennis S ChiBritta WeigeltJason A KonnerDmitriy Zamarin

Published in: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society (2022)

Our study suggests a potential role for immune checkpoint blockade in patients with clear cell carcinoma of the ovary. Identification of genetic and microenvironmental biomarkers predictive of response will be key to guide therapy.

Keyphrases

clear cell
genome wide
copy number
mesenchymal stem cells
gene expression
combination therapy
bone marrow