Lymphoblast transcriptome analysis in 22q11.2 deletion syndrome individuals with schizophrenia-spectrum disorder.

Elena MichaelovskyMiri CarmelDoron GothelfAbraham Weizman

Published in: The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry (2024)

Candidate pathways and upstream regulators may serve as novel biomarkers and treatment targets for SZ. Future transcriptome studies, including larger samples and proteomic analysis, are needed to substantiate our findings.

Keyphrases

spectrum disorder
bipolar disorder
gene expression
transcription factor
single cell
rna seq
current status
genome wide
replacement therapy