Login / Signup

Role of Inositol-Requiring Enzyme 1 and Autophagy in the Pro-Fibrotic Mechanism Underlying Graves' Orbitopathy.

Chae Eun LeeJi-Young KimJin Sook YoonJaeSang Ko
Published in: Yonsei medical journal (2024)
IRE1 mediates autophagy and the pro-fibrotic mechanism of GO, which provides a more comprehensive interpretation of GO pathogenesis and suggests potential therapeutic targets.
Keyphrases
  • endoplasmic reticulum stress
  • cell death
  • systemic sclerosis
  • idiopathic pulmonary fibrosis
  • signaling pathway
  • anti inflammatory
  • oxidative stress
  • human health