Non-immunological biomarkers for assessment of villous abnormalities in patients with celiac disease.
Alka SinghAnil K VermaPrasenjit DasShyam PrakashRaja PramanikB NayakSiddhartha Datta GuptaV SreenivasLalit KumarVineet AhujaGovind Kumar MakhariaPublished in: Journal of gastroenterology and hepatology (2019)
Plasma citrulline ≤ 30 μM/L is the most consistent, highly reproducible non-invasive biomarker that can predict the presence of villous abnormality and has the potential for avoiding duodenal biopsies in 78% patients suspected to have CeD.