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Adipose-Derived Mesenchymal Stem Cell Facilitate Hematopoietic Stem Cell Proliferation via the Jagged-1/Notch-1/Hes Signaling Pathway.

Hongbo WangXiaojuan BiRongyao ZhangHailong YuanJianli XuKaile ZhangSongqing QiXue ZhangMing Jiang
Published in: Stem cells international (2023)
may be mediated, at least in part, through the Jagged-1/Notch-1 signaling pathway. These findings provide valuable insights into the mechanisms underlying ADSCs-mediated hematopoietic support and may have implications for improving the treatment of PGF following HSCT.
Keyphrases
  • signaling pathway
  • hematopoietic stem cell
  • pi k akt
  • bone marrow
  • mesenchymal stem cells
  • epithelial mesenchymal transition
  • induced apoptosis
  • cell proliferation
  • stem cells
  • umbilical cord
  • combination therapy