Cross-comparison of systemic and tissue-specific metabolomes in a mouse model of Leigh syndrome.
Karin TerburghJeremie Z LindequeFrancois H van der WesthuizenRoan LouwPublished in: Metabolomics : Official journal of the Metabolomic Society (2021)
Our results confirm the value of urinary metabolomics when evaluating MD-associated metabolites, while cautioning against mechanistic studies relying solely on systemic biofluids.