Lysozyme 1 Inflamed CCR2 + Macrophages Promote Obesity-Induced Cardiac Dysfunction.

Lai Zhang Huian Han Andi Xu Adwait Amod SatheSiying FuJiaqi ZhaoWenhan Cai Yaqing YangJinting LiuHui BaiJingjing BenXudong ZhuXiaoyu LiQing YangZidun WangYayun GuChao Xing Gabriele G Schiattarella Steven Yan Cheng Hanwen Zhang Qi Chen

Published in: Circulation research (2024)

Our findings suggest that lysozyme 1 may represent a potential target for the diagnosis of obesity-induced inflammation and the treatment of obesity-induced heart disease.

Keyphrases

metabolic syndrome
insulin resistance
high glucose
diabetic rats
weight loss
type diabetes
oxidative stress
high fat diet induced
weight gain
drug induced
pulmonary hypertension
heart failure
physical activity
risk assessment
atrial fibrillation
climate change