Green-light-responsive metal-organic frameworks for colorectal cancer treatment.

Hannah D Cornell Yumeng ZhuStefan IlicNaomei E LidmanXiaozhou Yang John B Matson Amanda J Morris

Published in: Chemical communications (Cambridge, England) (2022)

Herein, the synthetic methods for preparation of a novel light-responsive metal-organic framework (MOF) UiO-AZB-F are outlined. Upon irradiation with green light, the framework demonstrates controlled release of chemotherapeutic drug cargo with simultaneous breakdown into low toxicity small molecule components.

Keyphrases

metal organic framework
small molecule
cancer therapy
oxidative stress
protein protein
mass spectrometry
molecularly imprinted
radiation induced
smoking cessation