Maternal Diet and the Serum Metabolome in Pregnancy: Robust Dietary Biomarkers Generalizable to a Multiethnic Birth Cohort.
Russell J de SouzaMeera ShanmuganathanAmel LamriStephanie A AtkinsonAllan BeckerDipika DesaiMilan GuptaPiush J MandhaneTheo J MoraesKatherine M MorrisonPadmaja SubbaraoKoon K TeoStuart E TurveyNatalie C WilliamsPhilip Britz-McKibbinSonia S AnandPublished in: Current developments in nutrition (2020)
Specific serum metabolites reflect intake of citrus fruit/juice, vegetables, animal foods, and nuts/legumes in pregnant women independent of ethnicity, fasting status, and delays to storage across multiple collection centers. Robust biomarkers of overall diet quality varied by cohort. Proline betaine, 3-methylhistidine, hippuric acid, TMAO, and tryptophan betaine were robust dietary biomarkers for investigations of maternal nutrition in diverse populations.