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Effects of antifungal stewardship using therapeutic drug monitoring in voriconazole therapy on the prevention and control of hepatotoxicity and visual symptoms: A multicentre study conducted in Japan.

Yukihiro HamadaTakashi UedaYoshitsugu MiyazakiKazuhiko NakajimaKeiko FukunagaTaiga MiyazakiNana Nakada-MotokawaMiki NagaoHideki KawamuraAkari ShigemiFumiya EbiharaToshimi KimuraKazuhiro IkegameMotoi UchinoHiroki IkeuchiYoshio Takesue
Published in: Mycoses (2020)
A significant preventive effect was demonstrated on hepatotoxicity, but not on visual symptoms because of earlier occurrence. With treatment modification after the occurrence of AEs, most patients completed therapy.
Keyphrases
  • end stage renal disease
  • risk assessment
  • ejection fraction
  • newly diagnosed
  • chronic kidney disease
  • drug induced
  • sleep quality
  • stem cells
  • mesenchymal stem cells