Target temperature management following cardiac arrest: a systematic review and Bayesian meta-analysis.
Anders ÅnemanSteven FrostMichael ParrMarkus B SkrifvarsPublished in: Critical care (London, England) (2022)
The posterior probability distributions did not support the use of TTM at 32-34 °C compared to 36 °C also including active control of fever to reduce the risk of death and unfavourable neurological outcome at 90-180 days. Any likely benefit of hypothermic TTM is smaller than targeted in RCTs to date.