Neutrophil trogocytosis during their trans-endothelial migration: role of extracellular CIRP.
Satoshi TakizawaYongchan LeeAsha JacobMonowar AzizPing WangPublished in: Molecular medicine (Cambridge, Mass.) (2022)
These data suggest that during the paracellular trans-endothelial migration of neutrophils in response to inflammation, eCIRP induces trogocytosis of neutrophils, and the trogocytosed neutrophils exhibit an exaggerated pro-inflammatory phenotype promoting acute lung injury.