Immunoglobulin recognition of fecal bacteria in stunted and non-stunted children: findings from the Afribiota study.
Kelsey E HuusAndré Rodriguez-PozoNathalie KapelAlison NestoretAzimdine HabibMichel DedeAmee MangesJean-Marc CollardPhilippe J SansonettiPascale VonaeschBarton Brett Finlaynull nullPublished in: Microbiome (2020)
Undernourished children carry a high load of intestinal pathogens and pathobionts. Our data suggest that stunted children have a greater proportion of IgA-recognized fecal bacteria. We moreover identify two putative pathobionts, Haemophilus and Campylobacter, that are broadly targeted by intestinal IgA. This study furthers our understanding of host-microbiota interactions in undernutrition and identifies immune-recognized microbes for future study.