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Immunoglobulin recognition of fecal bacteria in stunted and non-stunted children: findings from the Afribiota study.

Kelsey E HuusAndré Rodriguez-PozoNathalie KapelAlison NestoretAzimdine HabibMichel DedeAmee MangesJean-Marc CollardPhilippe J SansonettiPascale VonaeschBarton Brett Finlaynull null
Published in: Microbiome (2020)
Undernourished children carry a high load of intestinal pathogens and pathobionts. Our data suggest that stunted children have a greater proportion of IgA-recognized fecal bacteria. We moreover identify two putative pathobionts, Haemophilus and Campylobacter, that are broadly targeted by intestinal IgA. This study furthers our understanding of host-microbiota interactions in undernutrition and identifies immune-recognized microbes for future study.
Keyphrases
  • young adults
  • escherichia coli
  • dna methylation
  • pseudomonas aeruginosa
  • cancer therapy