Distinct B cell profiles characterise healthy weight and obesity pre- and post-bariatric surgery.
B ŠlisereM ArisovaO AizbalteM M SalmiņaM ZolovsM LevenšteinsM MukānsI TroickisL MeijaA LejnieksGuna BilandeE C RosserKristine OleinikaPublished in: International journal of obesity (2005) (2023)
Bariatric surgery patients display a unique B cell profile 6 months post-operatively; this bears minimal resemblance to that of pre-operative patients and only partially overlaps with that of lean controls. Post-operative differences in the B cell compartment compared to lean controls are detected despite global amelioration of inflammation and restoration of metabolic health. Collectively, this indicates that bariatric surgery creates a specific immunometabolic state with potential implications for health outcomes.
Keyphrases
- bariatric surgery
- weight loss
- end stage renal disease
- chronic kidney disease
- newly diagnosed
- ejection fraction
- obese patients
- public health
- healthcare
- metabolic syndrome
- type diabetes
- oxidative stress
- mental health
- skeletal muscle
- climate change
- adipose tissue
- postmenopausal women
- bone mineral density
- health information